History

2009
May In-licensed "Cationic Polyamino Acids" from the University of Tokyo and TOUDAI TLO, Ltd.
Mar Debiopharm S.A. started phase I clinical trial of DACH-platin Micelle (NC-4016) in EU.
2008
Dec Application of Nanoplatin® for Phase I/II study was approved in Taiwan
Sep Made license and co-development Agreement of Nanoplatin (NC-6004) with Orient Europharma Co., Ltd.
Apr Exclusive License Agreement signed with Toudai TLO, Ltd. on Incorporated Nucleic Acids into Micelles
Mar NanoCarrier got listed on the Tokyo Stock Exchanges Mothers
2007
Nov Nippon Kayaku Co., Ltd. started phase II clinical trail of Paclitaxel Micelle (NK105).
Oct Out-licensed Dach-Platin Micelle (NC-4016) to Debiopharm S.A.
Feb In-licensed “A new block copolymer for preparation of pH-sensitive polymeric micelle and a production process thereof” from the University of Tokyo and TOUDAI TLO, Ltd.
2006
Aug In-licensed “Physical trapping type polymeric micelle drug preparation”, for the research and development of paclitaxel micelle (NK105) with Japan Science and Technology Agency.
Jul Obtained exclusive license of “Electrostatic bonding type macromolecular micelle drug carrier and drug carried thereon” from TOUDAI TLO, Ltd.
Jun Entered into new joint agreement with Kirin Brewery Co., Ltd. (now Kirin Pharma Company, Limited) on the development of NC-4010 *.
May Started phase I clinical trial of Nanoplatin® (NC-6004) in U.K.
2005
Jul Formed partnership with TOUDAI TLO, Ltd for “discovery and development of drugs with high usability for treatment of solid cancers”.
Mar Formed partnership with Debiopharm S.A. for DACH-Platin micelle (NC-4016).
2004
Aug Moved head office and lab to Tohdai Kashiwa Venture Plaza in Kashiwa, Chiba.
May Nippon Kayaku Co., Ltd., a licensed company in Japan, started phase I clinical trial of Paclitaxel Micelle (NK105).
In-licensed “Coordinate complex of diaminocyclohexaneplatinum (II) with block copolymer containing poly (carboxylic acid) segment and antitumor agent comprising the same” from the University of Tokyo and TOUDAI TLO, Ltd.
2003
Jul Established Tokyo office in Chuo, Tokyo.
2002
Nov Formed partnership with Kirin Brewery Co., Ltd. (now Kirin Pharma Company, Limited) on the development of an Antibody-Linked Micelle (NC-4010).
Jun Out-licensed Paclitaxel Micelle to Nippon Kayaku Co., Ltd.
2001
Jan In-licensed “Polymeric micelle containing cisplatin enclosed therein and use thereof” from the Center for Advanced Science and Technology Incubation Ltd. (now TOUDAI TLO, Ltd.).
1999
Oct Moved head office to Tokatsu Techno Plaza in Kashiwa, Chiba, and established the lab.
1997
Aug Formed partnership with Nippon Oil & Fats Co., Ltd. (now NOF Corporation) on joint development and supply of a new block copolymer (after then, entered into a supply agreement on exclusive manufacture and supply of polymer on December 2003).
1996
Jun Founded in Setagaya, Tokyo, with the purpose of applying new block copolymers to develop pharmaceuticals and put them into practice.
* This is a new agreement, though its development code is the same as the joint research agreement entered into in November 2002. The active ingredient in the new agreement is different from that in the old one.