History

2011
Sep Worldwide license and co-development Agreement of Epirubicin Micelle (NC-6300) with KOWA company Ltd.
Jul Started phase Ⅱ clinical trial of Nanoplatin (NC-6004) in Taiwan&Singapore.
2010
Dec Collaborative research agreement with National Cancer Center to initiate a preclinical study of Epirubicin Micelle(NC-6300).
Oct Option agreement of protein micelle for rhFVIIa with LFB Biotechnologies.
Aug Nippon Kayaku Co., Ltd. started phase I clinical trail(Breast Cancer) of Paclitaxel Micelle (NK105).
2009
May In-licensed "Cationic Polyamino Acids" from the University of Tokyo and TOUDAI TLO, Ltd.
Mar Started phase I clinical trial of DACH-platin Micelle (NC-4016) in EU.
2008
Dec IND Application of Nanoplatin® for Phase I/II study was approved in Taiwan
Sep License and co-development Agreement of Nanoplatin (NC-6004) with Orient Europharma Co., Ltd.
Apr Exclusive License Agreement signed with Toudai TLO, Ltd. on Incorporated Nucleic Acids into Micelles
Mar NanoCarrier got listed on the Tokyo Stock Exchanges Mothers
2007
Nov Nippon Kayaku Co., Ltd. started phase II clinical trail(gastric cancer) of Paclitaxel Micelle (NK105).
Feb In-licensed “A new block copolymer for preparation of pH-sensitive polymeric micelle and a production process thereof” from the University of Tokyo and TOUDAI TLO, Ltd.
2006
Aug In-licensed “Physical trapping type polymeric micelle drug preparation”, for the research and development of paclitaxel micelle (NK105) with Japan Science and Technology Agency.
Jul Obtained exclusive license of “Electrostatic bonding type macromolecular micelle drug carrier and drug carried thereon” from TOUDAI TLO, Ltd.
May Started phase I clinical trial of Nanoplatin® (NC-6004) in U.K.
2005
Jul Formed partnership with TOUDAI TLO, Ltd for “discovery and development of drugs with high usability for treatment of solid cancers”.
Mar Formed partnership with Debiopharm S.A. for DACH-Platin micelle (NC-4016).
2004
Aug Moved head office and lab to Tohdai Kashiwa Venture Plaza in Kashiwa, Chiba.
May Nippon Kayaku Co., Ltd., a licensed company in Japan, started phase I clinical trial of Paclitaxel Micelle (NK105).
In-licensed “Coordinate complex of diaminocyclohexaneplatinum (II) with block copolymer containing poly (carboxylic acid) segment and antitumor agent comprising the same” from the University of Tokyo and TOUDAI TLO, Ltd.
2003
Jul Established Tokyo office in Chuo, Tokyo.
2002
Jun Out-licensed Paclitaxel Micelle to Nippon Kayaku Co., Ltd.
2001
Jan In-licensed “Polymeric micelle containing cisplatin enclosed therein and use thereof” from the Center for Advanced Science and Technology Incubation Ltd. (now TOUDAI TLO, Ltd.).
1999
Oct Moved head office to Tokatsu Techno Plaza in Kashiwa, Chiba, and established the lab.
1997
Aug Formed partnership with Nippon Oil & Fats Co., Ltd. (now NOF Corporation) on joint development and supply of a new block copolymer (after then, entered into a supply agreement on exclusive manufacture and supply of polymer on December 2003).
1996
Jun Founded in Setagaya, Tokyo, with the purpose of applying new block copolymers to develop pharmaceuticals and put them into practice.